skinsafecheck Ingredient Checker

Vitamin A Palmitate

Vitamin A palmitate is rated 2 to 3 on our list, a range whose top puts it in the moderate band, and the number is traced: Fulton 1989 graded it 1 to 3, varying with the supplier.

Like every rating here, it is for the raw ingredient tested alone, and a label does not print how much of it a product holds.

Is vitamin A palmitate comedogenic?

2–3 Moderate

Vitamin A Palmitate is rated 2–3 on the comedogenic scale: our list gives it a range from 2 to 3, and the band follows the 3 at the top.

An ester of vitamin A used in skincare. Fulton 1989 graded it 1 to 3, varying with the supplier.

Comedogenic rating
2–3 out of 5 (a range on our list)
Band
Moderate: Borderline plugging in the rabbit-ear test. Worth a look in a leave-on product.
Where the number comes from
Traced to Fulton 1989. The section on who rated it prints each grade.
Composition
Vitamin Derivative / Vitamins & Herbs
Also written as
No common variants recorded
Where Vitamin A Palmitate sits on the 0 to 5 comedogenic scale. Our list gives a range, so the whole range is drawn and the band follows the higher end. The papers we checked it against are under Sources we checked this rating against further down this page.

What a 2–3 means in practice

Three is the middle of the scale. Fulton 1989 counted 2 to 3 as borderline in the rabbit-ear test: some plugging of the follicles, short of a clear positive. Whether it matters depends on how high it sits on the label and whether the product stays on your skin.

Two things change what this number is worth. Ingredients are listed in descending order of concentration, so vitamin a palmitate near the top of a label matters far more than vitamin a palmitate at the bottom. And the rating describes the raw ingredient on its own. A 2006 review in the Journal of the American Academy of Dermatology found that a rating for a single ingredient does not reliably predict how a finished formula behaves on human skin. The full story of the scale is here.

Check a whole ingredient list

Who rated it

Our list gives vitamin a palmitate 2–3. These are the figures the published rabbit-ear studies we have read give it, as printed in each paper's table.

Paper Grade Tested as
Fulton 1989
rabbit ear, 10% in propylene glycol unless stated, two weeks
Grade 1 to 3, varying with the supplier Tested as Vitamin A palmitate

Our list's figure is within what these papers report.

A grade is for the raw ingredient tested alone on a rabbit's ear, which reacts more readily than human skin. It says nothing about how much of it a product holds or what the rest of the formula does.

Fungal acne

Vitamin A Palmitate matches rule 2, ester of a C12 to C24 fatty acid , on the fungal acne checker. An ester of palmitic acid, C16. The rule comes from lab studies of what Malassezia yeast can feed on, and it is not a verdict on any product.

Common questions

Is vitamin A palmitate comedogenic?
Vitamin A Palmitate is rated 2–3 on the comedogenic scale: our list gives it a range from 2 to 3, and the band follows the 3 at the top.
Is vitamin A palmitate non comedogenic?
No. Vitamin A Palmitate is rated 2–3 on the comedogenic scale, which is the moderate band. That is a published rating for the ingredient rather than a verdict on any product containing it.
What is vitamin A palmitate's comedogenic rating?
2–3 out of 5 on our list. It is classed as Vitamin Derivative / Vitamins & Herbs.

Sources we checked this rating against

  1. Kligman AM, Kwong T. “An improved rabbit ear model for assessing comedogenic substances.” British Journal of Dermatology, June 1979;100(6):699–702. (opens in a new tab) The rabbit-ear assay behind published 0 to 5 comedogenicity grades.
  2. Fulton JE Jr. “Comedogenicity and irritancy of commonly used ingredients in skin care products.” Journal of the Society of Cosmetic Chemists, November/December 1989;40(6):321–333. (opens in a new tab) Rabbit ear. Each ingredient at 10 percent in propylene glycol unless stated, applied five days a week for two weeks, and graded 0 to 5 from the width of the follicles, measured by micrometer and under the microscope. The paper counts 0 to 1 as not significant, 2 to 3 as borderline and 4 to 5 as positive. Some grades depended on the supplier of the raw material, and some oils were also tested refined.
  3. Draelos ZD, DiNardo JC. “A re-evaluation of the comedogenicity concept.” Journal of the American Academy of Dermatology, March 2006;54(3):507–512. doi:10.1016/j.jaad.2005.11.1058 (opens in a new tab) Tested finished products on the backs of six people and concluded that “Finished products using comedogenic ingredients are not necessarily comedogenic.”

The rating and description above are the ones this site publishes on its A–Z list. The papers above are the ones we checked it against, and the section on who rated it says whether any of them graded this ingredient.